Restylane Defyne Facial Filler

What is Restylane® Defyne?

As we age, our skin loses elasticity, and facial lines become more pronounced. Restylane Defyne treats deepening lines between the corners of your nose and around your mouth (called nasolabial folds).

Restylane Defyne offers cutting-edge technology that helps smooth out lines in your resting face while supporting your facial expressions. It produces natural-looking results and natural movement.

What Does Restylane Defyne Treat?

  • Moderate to deep smile lines (nasolabial folds)

  • Marionette lines (from the corners of the mouth downward)

  • Facial folds that need a bit more structural support


Restylane Defyne offers both softness and structure, giving you just the right amount of lift and flexibility so you look like yourself, only smoother.

Who Is It For?

Restylane Defyne is perfect for those who:

  • Have more pronounced facial lines but still want natural results

  • Want to maintain expressiveness while softening deeper folds

  • Appreciate a balance between support and flexibility

When deeper lines need attention, Restylane Defyne delivers. It’s designed to integrate with your facial movements, so you don’t just look younger—you look like you. Smooth, supported, and naturally confident.

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